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Capla comments on Fighting Mosquitos - Less Wrong
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Are there legal issues to intentionally driving species to extinction?
In this case the most efficient way seems to involve inserting a few genes into your new mosquitos to make them sterile. Releasing billions of gene-manipulated mosquitos into the wild isn't something you can do without government approval.
The most efficient method is to engineer a gene that make the mosquitoes that only produce male sperm. (Harder than engineering sterility, but there are many models to copy.) This might require only a single release. By the time it was noticed it would be a fait accompli.
Do mosquitoes even use an XY sex determination system?
So do, some don't. The first hit on google for mosquito sex determination says that a particular malaria mosquito does. The second talks about diversity.