James_Miller comments on Request for suggestions: ageing and data-mining - Less Wrong

14 Post author: bokov 24 November 2014 11:38PM

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Comment author: James_Miller 25 November 2014 01:08:52AM 1 point [-]

who consume a lower-than-typical amount of calories.

No. With intermittent fasting your total calorie consumption isn't necessarily below average, rather you have periods of time in which you either don't eat or only eat fats. I do what's called bulletproof intermittent fasting. One unexpected result is that I don't get colds anymore because, I think, of autophagy. I used to get about four a year and I have been doing the fasting for a little over two years so this result is significant.

Comment author: Andy_McKenzie 25 November 2014 09:26:32PM 1 point [-]

How do you postulate that autophagy reduces the risk of rhinovirus infection?

Comment author: James_Miller 25 November 2014 11:49:08PM 1 point [-]

I last took biology in high school so don't put too much trust in this or lower your opinion of me if this sounds silly, but: autophagy involves your body eating its own cells and your body is somehow smart enough to sometimes target harmful cells and therefore autography might be causing my body to destroy cells that get invaded by the rhinovirus infection.

Comment author: Andy_McKenzie 26 November 2014 04:04:49AM 0 points [-]

OK, fair enough. I generally think of autophagy as being within a cell, but perhaps virally infected cell compartments are more likely to be "eaten" under nutrient stress, or perhaps my application of the word autophagy is incorrect here.