As I'm sure you have considered, issues relating to racism and homophobia come into play.
Why? Is it rational to let them influence the issue in any way? In your personal value system, is a relatively heightened chance of dying from an infectious disease preferable to being thought of as racist or homophobic? How high does it have to get until that's no longer the case?
Source.
Moving my commentary to a separate comment, so as to disambiguate votes on my commentary and the original argument.