NancyLebovitz comments on An alarming fact about the anti-aging community - Less Wrong

30 Post author: diegocaleiro 16 February 2015 05:49PM

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Comment author: Vaniver 16 February 2015 08:06:36PM 9 points [-]

Two responses:

First, if this is a useful thing that we should be doing, good on you for making the case for it.

Second, it's not at all clear to me that this is a useful thing that we should be doing. What is the use case where I say "I'm glad I have those frozen cells from young me"? Egg freezing has obvious benefits given declining fertility with age, and unsurprisingly I see a significant infrastructure in place for freezing eggs. But for those of us that aren't women, that doesn't seem tremendously useful.

How big is the (expected) difference in success between, say, organs rebuilt with cells from a 25 year old to organs rebuilt with cells from a 45 year old? (If we don't know that, why are we saying the case for this as a life extension technology is "certain"?)

Comment author: NancyLebovitz 17 February 2015 04:14:21AM 0 points [-]

http://learn.genetics.utah.edu/content/epigenetics/twins/

It's possible to see quite a bit of epigenetic change in identical twins as they age. This doesn't necessary mean that those changes are deterioration, but it might be worth looking at what a person's base state is, or a least a younger state.