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Phigment comments on Harry Potter and the Methods of Rationality discussion thread, February 2015, chapter 111 - Less Wrong
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Is poison really a good attack against someone who holds the Philosopher's Stone?
Depends on the poison.
If it's something that prevents the poisoned person from noticing he has been poisoned, sure. Doesn't matter if you could fix the problem, if your brain has been prevented from realizing there IS a problem.
Alternately, if the "poison" is some sort of deleterious transfiguration effect upon the subject, which the stone will immediately make permanent, it would be hilarious. Snape, at least, thinks this way. Remember his attempt spike Voldemort's resurrection components with LSD?