Error comments on LW's take on nutrition? - Less Wrong
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I produce for you a book written by a relevant expert with ~2.5 times as many references as The China Study (2034 vs 758) who advocates eating an ancestral diet (lean unprocessed meat/fish, fruit, nuts, vegetables/root vegatables) (1). A list of individuals with relevant graduate degrees who more-or-less agree with him can be found in this list of speakers at a paleo conference he spoke at. His recommendations are at least as similar to the recommendations the Mayo clinic returned for me as Campbell's.
That is, I can make a symmetrical argument for a significantly different diet (2), complete with experts and evidence and stuff.
So, to address your questions directly: you should believe that nutrition is a young and complex field, and therefore shouldn't have everything all figured out; my take is that you may do well to replace grains with root vegetables, since that's something everyone agrees is good (plus they're really tasty!); this isn't good enough to inform your dietary choices because I just used a symmetrical argument for a diet that has nonnegligible discrepancies with the diet Campbell recommends; and I don't know how to dig out a signal that experts, to my knowledge, haven't managed to dig out without becoming an expert.
(FWIW, I spent about 5 years as a vegetarian, followed by 1.5 years doing the paleo thing, and now subsist entirely off DIY soylent, which combines the virtues of deriving all its protein from animal sources and being processed.)
(1) Interestingly, Campbell's and Lindeberg's diets can be eaten simultaneously, and this intersection is 100% in-line with what the Mayo clinic recommended me. The difference is that Campbell allows grains and beans, and Lindeberg allows (unprocessed) lean meats, fish, and eggs.
(2) Again, there's substantial overlap, but also substantial disagreement: Lindeberg, for instance, observe the Inuit derive something like 98% of their calories from animal sources and are virtually untouched by Western disease, and concludes that very high consumption of (unprocessed) animals is perfectly fine, whereas Campbell claims that humans should eat minimal amounts of animal.
Just how genetically isolated are the Inuit?
I am thinking of things like the evolution of adult lactose tolerance, and wondering if what's good for the Inuit might be different from what's good for the rest of us. I'd expect the ability to consume large amounts of meat without ill effects would be pretty powerfully selected for, in an environment where nearly all calories come from meat.
The selective pressure on being able to digest lactose as an adult is stronger than the selective pressure to not develop heart disease from eating too much meat, since the former kills you before you can reproduce. Lindeberg claims that humans have sufficiently recent common ancestry that, in absence of the kill-you-before-you-reach-childbearing-age selective pressures, we're able to generalize from group-to-group fairly well. Non-Inuit probably do worse than Inuit on Inuit diets, and bool is_Inuit is a useful input in a program to produce an optimal soylent blend for someone, but the selective pressure isn't strong enough for the Inuit to be mostly devoid of heart disease [1] simply because it was selected for.
Also, many other hunter-gatherers from all over eat large amounts of meat (though as much as the Inuit) and are just as devoid of Western disease as are the Kitavans, who consume relatively little, which supports the hypothesis that Inuit aren't mostly devoid of heart disease because they're genetically unusual.
[1] IIRC Inuit do suffer from slightly more Western disease than Kitavans (most calories from plants), but not by a very impressive margin.