Short answer is I don't know. The long answer will take a little background.

I haven't bothered to read through Decoy's internals, but this sort of steganography usually hides its secret data in the least significant bits of the decoy image. If that data is encrypted (assuming no headers or footers or obvious block divisions), then it will appear to an attacker like random bytes. Whether or not that's distinguishable from the original image depends on whether the low bits of the original image are observably nonrandom, and that's not something I know offhand -- although most images will be compressed in some fashion and a good compression scheme aims to maximize entropy, so that's something. And if it's mostly random but it does fit a known distribution, then with a little more cleverness it should be possible to write a reversible function that fits the encrypted data into that distribution.

It will definitely be different from the original image on the bit level, if you happen to have a copy of it. That could just mean the image was reencoded at some point, though, which is not unheard of -- though it'd be a little suspicious if only the low bits changed.