[Link] Persistence of Long-Term Memory in Vitrified and Revived C. elegans worms

Rangi

http://online.liebertpub.com/doi/pdf/10.1089/rej.2014.1636

This is a paper published in 2014 by Natasha Vita-More and Daniel Barranco, both associated with the Alcor Research Center (ARC).

The abstract:

Can memory be retained after cryopreservation? Our research has attempted to answer this long-standing question by using the nematode worm Caenorhabditis elegans (C. elegans), a well-known model organism for biological research that has generated revolutionary findings but has not been tested for memory retention after cryopreservation. Our study’s goal was to test C. elegans’ memory recall after vitrification and reviving. Using a method of sensory imprinting in the young C. elegans we establish that learning acquired through olfactory cues shapes the animal’s behavior and the learning is retained at the adult stage after vitrification. Our research method included olfactory imprinting with the chemical benzaldehyde (C₆H₅CHO) for phase-sense olfactory imprinting at the L1 stage, the fast cooling SafeSpeed method for vitrification at the L2 stage, reviving, and a chemotaxis assay for testing memory retention of learning at the adult stage. Our results in testing memory retention after cryopreservation show that the mechanisms that regulate the odorant imprinting (a form of long-term memory) in C. elegans have not been modified by the process of vitrification or by slow freezing.

http://online.liebertpub.com/doi/pdf/10.1089/rej.2014.1636

This is a paper published in 2014 by Natasha Vita-More and Daniel Barranco, both associated with the Alcor Research Center (ARC).

The abstract:

Can memory be retained after cryopreservation? Our research has attempted to answer this long-standing question by using the nematode worm Caenorhabditis elegans (C. elegans), a well-known model organism for biological research that has generated revolutionary findings but has not been tested for memory retention after cryopreservation. Our study’s goal was to test C. elegans’ memory recall after vitrification and reviving. Using a method of sensory imprinting in the young C. elegans we establish that learning acquired through olfactory cues shapes the animal’s behavior and the learning is retained at the adult stage after vitrification. Our research method included olfactory imprinting with the chemical benzaldehyde (C₆H₅CHO) for phase-sense olfactory imprinting at the L1 stage, the fast cooling SafeSpeed method for vitrification at the L2 stage, reviving, and a chemotaxis assay for testing memory retention of learning at the adult stage. Our results in testing memory retention after cryopreservation show that the mechanisms that regulate the odorant imprinting (a form of long-term memory) in C. elegans have not been modified by the process of vitrification or by slow freezing.

'Comrades, good news. You are free to research and publish anything you want about capitalist economics, as long as it's negative and does not endorse or practice it. Let 100 flowers bloom!'

The ban is only for members of the Society for Cryobiology and concerns supporting human cryopreservation. I don't see how experiments on worms would have anything to do with it.

Are you arguing that despite bitter hatred and an astonishing policy outright banning cryonics, this has zero influence on the notoriously politicized, inconsistent, random, risk-averse scientific publication process which has been amply documented to settle for lowest common denominators, punish ambitious work, express peer reviewers' personal prejudices in discriminating against minorities, conservatives, etc? You think that somehow cryonics papers will be an exception to all this, will get a free pass and be fairly and impartially evaluated by its sworn enemies?

Oh you're right. And in the related news, global warming doesn't exist, evolution is a hoax, vaccines cause autism, etc...

The ban's obvious rationale is that cryobiologists believe that cryonics is a pseudo-scientific practice and they don't want the reputation of their field to be tarnished by association with it.

You seem to claim that the ban is a matter of personal or tribal hatred and cryobiologists are acting like a religious cult trying to do everything in its power to undermine the heretics even by suppressing perfectly good cryobiology research.
As I said, this is a very serious allegation and it should be backed by evidence.

Dismissing the lack of scientific publications in favor for your pet position by accusing mainstream scientists of being biased is an overly general argument that could be used and is in fact used to support every crackpot theory out there.

I don't see how experiments on worms would have anything to do with it.

Now you are playing dumb. We are talking about chilling effects, and there are not that many cryobiologists (or cryonicists, for that matter). Everyone has gotten the message sent by the ban.

Oh you're right. And in the related news, global warming doesn't exist, evolution is a hoax, vaccines cause autism, etc...

What on earth are you talking about? The ban is right there in the bylaws. I don't need to misinterpret any hacked emails to talk about it or make up data like Wakefield d... (read more)

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[Link] Persistence of Long-Term Memory in Vitrified and Revived C. elegans worms

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[Link] Persistence of Long-Term Memory in Vitrified and Revived C. elegans worms

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