gwern comments on Systemic review of antidepressants vs placebo commentary - Less Wrong

0 Post author: michael_b 03 June 2015 12:40PM

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Comment author: gwern 03 June 2015 06:37:44PM 0 points [-]

Probably but the use and interpretation of blinding indexes is still a bit controversial. For example, the 2001 CONSORT guidelines suggested using and reporting a blinding index but the latest 2010 version dropped it, saying:

Item 11 (blinding)—We added the specification of how blinding was done and, if relevant, a description of the similarity of interventions and procedures. We also eliminated text on “how the success of blinding (masking) was assessed” because of a lack of empirical evidence supporting the practice, as well as theoretical concerns about the validity of any such assessment (23, 24).