Indians call sterile mosquitos CIA agents (Washington Post, December 10, 1974).
"The history of genetic control trials against culicine mosquitoes in India in the mid-1970s shows how opposition can have far-reaching consequences. After several years of work on field testing of the mating competitiveness of sterile male mosquitoes, accusations that the project was meant to obtain data for biologic warfare using yellow fever were launched in the press and taken up by opposition politicians. Shortly afterward, a well-prepared attempt to eradicate an urban Ae. aegypti population by sterile male releases was banned by the government of India 2 days before its launch." (x)
In 1987, a book (“Once Again About the CIA”) was published by Novosti, with the quote: "The CIA Directorate of Science and Technology is continuously modernizing its inventory of pathogenic preparations, bacteria and viruses and studying their effect on man in various parts of the world. To this end, the CIA uses American medical centers in foreign countries. A case in point was the Pakistani Medical Research Center in Lahore… set up in 1962 allegedly for combating malaria." (x)
Genetically modified mosquitoes set off uproar in Florida Keys - "A lot of people just don't trust the FDA and this private company to tell us the truth"
I really wish that having military/intelligence operatives pose as aid workers or humanitarian workers even outside of war was treated similar to a war crime.
The world is basically [food secure, except Africa](http://blog.givewell.org/2009/03/16/can-the-green-revolution-be-repeated-in-africa).
Things [aren't improving the way people hope](http://www.givewell.org/international/technical/additional/Easterly-paper).
The Gates Foundation [can't spend their way out of this problem the traditional way](http://blog.givewell.org/2009/10/29/gates-foundation-on-agriculture-funding-where-are-the-facts/).
What's to be done?
Reading up on the GiveWell Open Philanthropy Project's investigation of science policy lead me to look up CRISPR which is given as the example of a very high potential basic science research area.
In context, Givewell appears to be interested in the potential for Gene drive. I am not sure if I am using the term in a grammatically correct way.
I would be suprised if I am the first community member to ponder whether we could just go ahead and exterminate mosquito's to control their populations. Google research I conducted ages ago indicated that doing so resulted in no effective improvement in desired outcomes over the long term. I vaguely remember several examples cited, none of which were Gene Driving, which I have only just heard of. I concluded, at the time, that controlling mosquito populations wasn't the way to go, and instead people should proactively protect themselves.
It's apparent that research is emerging for the efficacy of Gene Driving. In conducting research for this discussion post, I found most webpages in top google results were from groups and individuals concerned about genetically modified mosquitos being released. I am interested in know if that's the case for anyone else, since my results may be biased by google targeting results based on my past proclivity for using google-searching to confirm suspicions about things I already had.
It appears that the company responsible for the mosquitos is called Oxitec. I have no conflict of interest to disclose in relation to them (though I was hoping to find one, but they're not a publicly listed company!). They appear to be supplying trials in the US and Australia. Though, I haven't looked to see if they're involved in any trials in developing countries. It stuns me that I was not aware of them, given multiple lines of interest that could have brought me to them.
My general disposition towards synthetic biology has been overwhelming suspicious and censorial in the recent past. My views were influenced by the caution I've ported from fears of unfriendly AI. I wanted to share this story of Gene Driving because it is heartwarming and has made me feel better about the future of both existential risk and effective giving.
Edit: Synthetic biology for fun and profit! Any biohackers around? I just discovered the [registry of standard biological parts](http://parts.igem.org/Main_Page?title=Main_Page), the [biobrick assembly kit](https://www.neb.com/products/e0546-biobrick-assembly-kit) and [genome compiler](http://www.genomecompiler.com/?_ga=1.251739919.769837041.1438856618). I'm having the biggest nerdgasms I can recall. Who wants to chlorinate the mosquito gene pool with me?
Synthetic biology for good: So who's gonna do the protocol design for the tsetse fly gene drive? Whose gonna model the disease?
How much would it cost? [Here's an esteimate](http://lesswrong.com/lw/mld/genosets/cnys). Seems like an easy investment decision in public wellbeing.