A satisfactory solution should also work if the em population explodes to several quadrillion. As I said, 'all sorts of questionable issues'; it's a rule-of-thumb to keep certain troubling edge cases from being quite so troublesome, not a fixed axiom to use as the foundation for an ethical system that can be used by all sapient beings in all circumstances. Once I learn of something more coherent to use instead of the rule-of-thumb, I'll be happy to use that something-else instead.
Summary: the problem with Pascal's Mugging arguments is that, intuitively, some probabilities are just too small to care about. There might be a principled reason for ignoring some probabilities, namely that they violate an implicit assumption behind expected utility theory. This suggests a possible approach for formally defining a "probability small enough to ignore", though there's still a bit of arbitrariness in it.