So we have nothing to worry about plants humans consumed for millenia -- like Cannabis sativa and Papaver somniferum?
Unless chemists start concentrating the relevant chemical, or they're used by people whose ancestors haven't had millennia to adept to them. Yes, this applies to alcohol as well.
India vs. Pakistan: the nuclear option is dangerously close, and nobody seems to want to prevent it
http://qz.com/541502/a-nuclear-war-between-india-and-pakistan-is-a-very-real-possibility/