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DanielLC comments on Open thread, Nov. 16 - Nov. 22, 2015 - Less Wrong
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Um, no, we cannot colonise the stars with current tech. What a surprise! We cannot even colonise mars, antarctica or the ocean floor.
Of course you need to solve bottom up manufacturing (nanotech or some functional eqivalent) first, making you independent from eco system services, agricultural food production, long supply chains and the like. This also vastly reduces radiation problems and probably solves ageing. Then you have a fair chance.
So yes, if we wreck earth the stars are not plan B, we need to get our shit together first.
If at this point there is still a reason to send canned monkeys is a completely different question.
Alternately, learn to upload people. Which is still probably going to require nanotech. This way, you're not dependent on ecosystems because you don't need anything organic. You can also modify computers to be resistant to radiation more easily than you can people.
If we can't thrive on a wrecked Earth, the stars aren't for us.