johnlawrenceaspden comments on A Medical Mystery: Thyroid Hormones, Chronic Fatigue and Fibromyalgia - Less Wrong

23 Post author: johnlawrenceaspden 14 February 2016 01:14PM

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Comment author: Romashka 31 January 2016 07:10:29PM *  2 points [-]

Buskila, Sarzi-Puttini and Ablin in their paper The genetics of fibromyalgia syndrome (Pharmacogenomics, 8(1) 67-74) say it is probably polygenic, so perhaps there is significant overlap in the genes making people more likely to get either of the disorders. (I only read the abstract.)

Comment author: johnlawrenceaspden 31 January 2016 07:35:53PM 1 point [-]

Damn, I can only see the abstract. I'd like to see that paper if anyone has a copy.

They seem to be fingering endocrine genes, but adrenal rather than thyroid. A lot of alternative medicine people talk about 'adrenal fatigue' in this context, but I hadn't been paying much attention to that since 'real' doctors don't think it's a thing.

But I don't know what I'm talking about! Can anyone who does read that paper and tell us what it means?

Comment author: Magnap 14 February 2016 02:29:01PM 2 points [-]

Both the paper and an update to it can be found quite easily on Library Genesis.

Comment author: johnlawrenceaspden 15 February 2016 08:50:42PM 1 point [-]

Ooh, that is an interesting site. Thankyou. Paper downloaded and will read.