johnlawrenceaspden comments on A Medical Mystery: Thyroid Hormones, Chronic Fatigue and Fibromyalgia - Less Wrong

23 Post author: johnlawrenceaspden 14 February 2016 01:14PM

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Comment author: buybuydandavis 25 February 2016 12:14:25AM *  1 point [-]

Not a depressive crash, but a sudden and totally unexpected intensification of my normal emotions over the last few days... No hyper symptoms at all.

That's a better description of what I experienced. It was depression in the sense of an intensification of anxiety and sadness, not in the sense of lethargy and apathy. Also, I think I was having heart palpitations.

The thing is, I think the symptoms you list are Hyper symptoms. I googled HYPERthyroid symptoms, and sometimes saw mentions of bipolar, crying fits, and mood swings, along with the usual heart palpitations and anxiety.

I wonder if sudden increases in thyroid levels at low basal levels can have some of the same effects as long term high basal levels. That's consistent with some models of psychiatric meds - at low basal levels, you're upregulated to compensate, so that initial bumps are equivalent to high basal levels until your system downregulates.

I don't mean to feed the obsession, but at the time the worst aspect was feeling in the grips of some psychological problem I didn't understand, instead of merely just having a reaction to meds. As I hazily recall, I think I backed off on the dosage and the symptoms went away a few days thereafter.

Take care of yourself.

Oh. Just got some lab work back. TSH down to 2.2. T3 mid range. DHEA/Progesterone/T/E2 all right where I want them (I'm big on life extension and HRT). Yay!

Comment author: johnlawrenceaspden 29 February 2016 10:34:35PM 0 points [-]

Dan, again I hear you and agree. I thought I was being so careful. What a fool I am.

Good luck! Be careful. Note the awe-inspiring lack of smugness with which I pretend to greet your news.