Omega lets me decide to take only one box after meeting Omega, when I have already updated on the fact that Omega exists, and so I have much better knowledge about which sort of god I'm likely to encounter. Upsilon treats me on the basis of a guess I would subjunctively make without knowledge of Upsilon. It is therefore not surprising that I tend to do much better with Omega than with Upsilon, because the relevant choices being made by me are being made with much better knowledge. To put it another way, when Omega offers me a Newcomb's Problem, I will condition my choice on the known existence of Omega, and all the Upsilon-like gods will tend to cancel out into Pascal's Wagers. If I run into an Upsilon-like god, then, I am not overly worried about my poor performance - it's like running into the Christian God, you're screwed, but so what, you won't actually run into one. Even the best rational agents cannot perform well on this sort of subjunctive hypothesis without much better knowledge while making the relevant choices than you are offering them. For every rational agent who performs well with respect to Upsilon there is one who performs poorly with respect to anti-Upsilon.

On the other hand, beating Newcomb's Problem is easy, once you let go of the idea that to be "rational" means performing a strange ritual cognition in which you must only choose on the basis of physical consequences and not on the basis of correct predictions that other agents reliably make about you, so that (if you choose using this bizarre ritual) you go around regretting how terribly "rational" you are because of the correct predictions that others make about you. I simply choose on the basis of the correct predictions that others make about me, and so I do not regret being rational.

And these questions are highly relevant and realistic, unlike Upsilon; in the future we can expect there to be lots of rational agents that make good predictions about each other.