You're not accounting for the costs of investigating the prediction market itself. Perhaps if it was well known to be an extremely liquid market where I could be sure my bets would pay off. But I'm busy right now working on my start up, and even looking into the question will have a high opportunity cost.
My friend did a great job of arbitrage on the 2004 election, and made like $250 dollars. He would have made a lot more, but the market simply wasn't liquid enough to support it (he bought up all the contracts anyone would sell). It took him probably 5 hours to examine the market, find the arbitrage, and place the bets.
My wage consulting would be at least $100/hour. So it simply doesn't make sense to play in a market where, even if you realize the market is way out of whack, there simply isn't enough money in play to pay better than $50/hour.
The Intrade prediction market is giving Hillary a 53% chance and Obama a 47% chance of winning the Democratic presidential nomination. Hillary is down 7.5 percentage points in just the last day. (Note: Between when I wrote the above, and when I posted this, Hillary went up to 54.)
From what I've read on Intrade, you can fund your account with up to $250 using a credit card, and it should land in your account immediately. (More than this takes time.) Also, remember that you can sell contracts at any time afterward - you don't have to wait months to collect your payout.
If you think that Hillary is going to do better than the polls on Super Tuesday, and you're going to sneer afterward and say that Intrade was "just tracking the polls", buy Hillary now.
If you think that Obama is going to do better than the polls on Super Tuesday, and you're going to gloat about how prediction markets didn't call this surprise in advance, buy Obama now.
If you don't do either, then clearly you do not really believe that you know anything the prediction markets don't. (Or you don't understand expected utility, or your utilities over final outcomes drop off improbably fast in the vicinity of your current wealth minus fifty bucks - you don't have to bet the full $250.) It is free money, going now for anyone who genuinely thinks they know better than the prediction markets what will happen next.
Prediction markets do not have supernatural insight. If they give the candidates fifty-fifty odds, it means that the market collectively doesn't know what will happen next. Even if you're well-calibrated, you get surprised on 90% probabilities one time out of ten.
The point is not that prediction markets are a good predictor but that they are the best predictor. If you think you can do better, why ain'cha rich? Any person, group, or method that does better can pump money out of the prediction markets.
If prediction markets react to polls, they're getting new information, that they didn't predict in advance, which happens. Being the best predictor doesn't make you omniscient.
Everyone's going to find it real easy to make a better prediction afterward, but if you think you can call it in advance, there's FREE MONEY GOING NOW.
Buy now, or forever hold your peace.