turchin comments on The map of the risks of aliens - Less Wrong
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There is also the risk of a non--AI wave, another panspermia event.
If there were another wave of optimized bio-life that is tracking on the galactic wind, we could be inundated with a fast growing, and very flexible life forms that could maybe fill all biological niches, or uptake all free nutrients.
Outcompeted in evolution by a microbe would be distressing...
I think the real risk is only in the case that is space grey goo based on nanobots. In your case it is almost the same, but biologically based.