"When I was one-and-twenty / I heard a wise man say, / 'Give crowns and pounds and guineas / But not your heart away; / Give pearls away and rubies / But keep your fancy free.' / But I was one-and-twenty, / No use to talk to me."
meta-analysis of intelligence GCTAs, limits set by measurement error, current polygenic scores, possible gains with current IVF procedures, the benefits of selection on multiple complex traits, the possible annual value in the USA of selection & value of larger GWASes, societal consequences of various embryo selection scenarios, embryo count versus polygenic scores as limiting factors, comparison with iterated embryo selection, limits to total gains from iterated embryo selection etc.
"When I was one-and-twenty / I heard a wise man say, / 'Give crowns and pounds and guineas / But not your heart away; / Give pearls away and rubies / But keep your fancy free.' / But I was one-and-twenty, / No use to talk to me."
My past year of completed writings, sorted by topic:
Genetics:
AI:
Reinforce.jsdemoBiology:
Statistics:
Cryptography:
Misc:
gwern.netitself has remained largely stable (some CSS fixes and image size changes); I continue to use Patreon and send out my newsletters.