I occasionally experience this, but I've never assigned it strong positive or negative affect/valence. I'm high in openness to experience, so I just kinda thought it was an academically interesting phenomenon, and haven't thought much of it, much less lost any sleep over it. It's just interesting in the same way that this is interesting.

If anyone takes it too seriously, I recommend this approach. Just clicking the xkcd link will help your brain more strongly associate the humorous and fascinating bits about it with the call of the void. I recommend trying to set up a Trigger Action Plan, so that you think of the xkcd any time you experience the call of the void.