I might be a bit late with this, but here's my 2 cents:
"Maybe spend another month or two doing large transhumanist sequences, either on the Singularity Institute blog (currently fairly defunct) or here on Overcoming Bias if the readers really want that."
I suggest writing the Transhumanist stuff on either a new blog (wordpress.com is free and easy to set up) or the SIAI blog, and link that prominently from Overcoming Bias. Maybe even do a weekly roundup/linkfest post here to remind people.
This would mean that you wouldn't lose those who are interested, and that those who aren't can easily skip it and spare us the complaining.
One million cumulative daily visits! Woot n' stuff. Also we're in the top 5,000 of all blogs on Technorati, and one of the top 10 econblogs by Technorati rank.
Seems like a good time to mention that I'll be appearing at Penguicon, a combination open-source/science-fiction convention in Troy, MI, Apr 18-20, as a Nifty. I'll be doing an intro to Bayesian reasoning that you probably don't need if you're reading this, possibly a panel on the Virtues of a Rationalist, some stuff on human intelligence upgrades, and definitely "The Ethics of Ending the World" with Aaron Diaz (Dresden Codak).
After the jump, you can see some proposed cover art for the blook.
For the benefit of the humor impaired: Yes, this is a joke. Erin, my girlfriend, Photoshopped this when she heard I was planning to do a book.
This is all taking longer than I expected - as expected - but I do think I'm getting there.
My current serious strategy for the blook is as follows:
If you've got more experience in the publishing industry and you see some reason that any of this won't work, i.e., "No one will talk to you if you've ever done anything with Wowio or Lulu" or "Today's readers don't want short popular books, they want 500-page tomes" or something like that, please email me or comment.