Consider the hypothesis:

On August 1st 2008 at midnight Greenwich time, a one-foot sphere of chocolate cake spontaneously formed in the center of the Sun; and then, in the natural course of events, this Boltzmann Cake almost instantly dissolved.

I would say that this hypothesis is meaningful and almost certainly false. Not that it is "meaningless". Even though I cannot think of any possible experimental test that would discriminate between its being true, and its being false.

I would say that this hypothesis is meaningful and almost certainly false. Not that it is "meaningless". Even though I cannot think of any possible experimental test that would discriminate between its being true, and its being false.

Well, if you had access to a time machine and some sensing device that could survive the environment of the Sun...

Yeah, I'm a nitpicker. I'm also not as good at picking nits as I might like.