I would not, or at least probably would not. For sufficiently drastic survival ratio, I might. I would not, because humor and art are tied far too directly into the sense of fun; an excellent game is art just as much as Guernica, Citizen Kane, or a Beethoven symphony, and losing that entire section of the aesthetic sense would spoil too many fun things.

Of course, whatever senses replaced our senses of art/humor might bring other, equal fun with them. In which case I'd be more inclined to accept the deal.