Recently the Large Hadron Collider was damaged by a mechanical failure. This requires the collider to be warmed up, repaired, and then cooled down again, so we're looking at a two-month delay.
Inevitably, many commenters said, "Anthropic principle! If the LHC had worked, it would have produced a black hole or strangelet or vacuum failure, and we wouldn't be here!"
This remark may be somewhat premature, since I don't think we're yet at the point in time when the LHC would have started producing collisions if not for this malfunction. However, a few weeks(?) from now, the "Anthropic!" hypothesis will start to make sense, assuming it can make sense at all. (Does this mean we can foresee executing a future probability update, but can't go ahead and update now?)
As you know, I don't spend much time worrying about the Large Hadron Collider when I've got much larger existential-risk-fish to fry. However, there's an exercise in probability theory (which I first picked up from E.T. Jaynes) along the lines of, "How many times does a coin have to come up heads before you believe the coin is fixed?" This tells you how low your prior probability is for the hypothesis. If a coin comes up heads only twice, that's definitely not a good reason to believe it's fixed, unless you already suspected from the beginning. But if it comes up heads 100 times, it's taking you too long to notice.
So - taking into account the previous cancellation of the Superconducting Supercollider (SSC) - how many times does the LHC have to fail before you'll start considering an anthropic explanation? 10? 20? 50?
After observing empirically that the LHC had failed 100 times in a row, would you endorse a policy of keeping the LHC powered up, but trying to fire it again only in the event of, say, nuclear terrorism or a global economic crash?
We're not talking about all of science. (Though I stand by my claim that he started it, unless you can point to someone else writing down a workable scientific method beforehand.) We're talking about whether or not anthropic reasoning tells us to expect to see people building the LHC, at a cost of $1 billion per year.
Thatcher apparently rejected the idea as presented, and rightly too if the Internet accurately reported the pitch they made to her. (In this popular account, the Higgs mechanism doesn't "explain mass," it replaces one arbitrary number with another! I still don't know the actual reasons for believing in it!) So we don't need to imagine humanity dying out, and we don't need to assume that civilization collapses after using up irreplaceable fossil fuels. (Though that one seems somewhat plausible.) I don't think we even need to assume religious tyranny crushes respect for science. Slightly less radical changes to the culture of a small fraction of the world seem sufficient to prevent the LHC expenditure for the foreseeable future. Add in uncertainty about various risks that fall short of total annihilation, and this certainty starts to look ridiculous.
Now as I said, one could make a different anthropic argument based on population in various 'worlds'. But as I also said, I don't think we know enough to get a high probability from that either.
Hakob Barseghyan teaches in his History and Philosophy of Science course that Descartes started it. The hypothetico-deductive method (what's commonly called the scientific method) is a result of the philosophic commitments of Descartes thought.