Richard_Hollerith comments on Which Parts Are "Me"? - Less Wrong
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I cannot recall ever trying to delete or even control a large part of myself, so no opinion there, but "distancing ourselves from ourselves" sounds a lot like developing what some have called an observing self, which is probably a very valuable thing for an person wishing to make a large contribution to the world IMHO.
A person worried about not feeling alive enough would probably get more bang for his buck by avoiding exposure to mercury, which binds permanently to serotonin receptors, causing a kind of deadening.