Eh, Lanier has some sound intuitions but his arguments supporting them seem confused. I am (naturally) more impressed with my own arguments against reductionism, some of which are collected here. My attempts to argue them around here have mostly come to naught though.

Also, you should read some Brian Cantwell Smith.

You owe it to yourself to take on the strongest arguments against your position as well as the weak ones. I don't know where my half-assed speculations fit in, but Smith is a serious thinker who, like you and Lanier, comes out of the computational world so you ought to at least be able to connect on some level.