An well-trodden point from my perspective - but de Grey's list of damage makes no mention of pathogens. Yet a number of types of pathogens are long-lived entities that accumulate and eventually do you in. So: a pathogen plan is needed - and dealing with pathogens is not an easy problem.
My latest on Bloggingheads.tv is up. BHTV wanted someone to interview Aubrey de Grey of the Methuselah Foundation about basic research in antiagathics, and they picked me to do it. It made the interview somewhat difficult, since Aubrey and I already agree about most things, but we managed to soldier on. The interview is mostly Aubrey talking, as it should be.