Nick_Tarleton comments on Building Weirdtopia - Less Wrong
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Taken to a literal extreme (I don't know if that's your intent), the idea that pain is necessary for pleasure violates the Generalized Anti-Zombie Principle, or something like it. If pleasure without contrast palls, there's some neurological reason for this, one that we could work around in wireheading if we really wanted to. I think the most you can plausibly say is that for humanlike architectures, memories of suffering (not necessarily true ones) are necessary to appreciate pleasures more complex than heroin.
Personally, though, I think that there are already plenty of humans who, through genetics and/or introspective self-modification, can be perfectly happy without improving conditions.