I don't know if this is a little too afar field for even a Discussion post, but people seemed to enjoy my previous articles (Girl Scouts financial filings, video game console insurance, philosophy of identity/abortion, & prediction market fees), so...
I recently wrote up an idea that has been bouncing around my head ever since I watched Death Note years ago - can we quantify Light Yagami's mistakes? Which mistake was the greatest? How could one do better? We can shed some light on the matter by examining DN with... basic information theory.
Presented for LessWrong's consideration: Death Note & Anonymity.
It does give different answers for problems like the Prisoner's Dilemma when your opponent is similar enough to you that they will make the same decisions. As you mentioned, it makes an appearance in HP:MoR for similar reasons. There's no obvious application to Death Note, but I think it could certainly be incorporated somehow. If you've seen the film Memento, you might have some idea of what I mean. (I don't want to spoil Death Note because it really is an excellent anime series, so I'm not going to say exactly what I was thinking.) TDT is certainly not essential to rationality but it is very interesting, so it might be worth including in a Death Note re-write for that reason alone.