I don't feel like starting/finding a conversation elsewhere about the comic, but for the record, I'm still unconvinced by the arguments I've heard against quantum (or modal-realist, or eternal-recurrence) immortality. (I haven't read the paper linked here, though.) I realize few of the "me"s that would result from that kind of transition would have much in common with me-today, but I think I can live with that. It's harder to live with the fact that a lot of me will be as badly off as factory-farmed animals or worse, but there's not much I can do about that beyond trying to reduce the measure of conditions like that in general, which I have limited ability and will to do.

I also hold out hope for some kind of repeated quantum suicide for "free" energy after we run out, or (slightly more dubiously) a Permutation City scenario.

I'm not particularly optimistic about unknown physics, or (edit 10/22) convincing the simulators to let us out, and (edit 11/25) the Omega Point is of course bunk.