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Matt_Simpson comments on What topics would you like to see more of on LessWrong? - Less Wrong Discussion
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Statistics - we've had a few posts on those, but some intro posts could be nice, or some discussion of things like principal component analysis, statistical signficance, misuses of statistics, etc.
(by comparison, it seems like we've had maybe three different introductions to decision theory, even though it's a topic of less general use)
In the near future, I plan to write a somewhat detailed discussion of the JAMA paper on vitamins that Phil Goetz and Robin Hanson have written about.
At some point I also plan to write an essay on what statistical models are actually models of and the implications for actually doing statistics, just to make sure I thoroughly work out the ideas. When I do, I'll probably post it here for anyone who's interested.
(Posting this to make it more likely that I actually do these things)