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Eneasz comments on Should I be afraid of GMOs? - Less Wrong Discussion
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In principle they have awesome potential. My only current concern is that currently one of the major applications is making crops more pesticide-resistant, which is leading to a huge increase in pesticide use with some potential for toxicity.
http://thelastpsychiatrist.com/2010/06/pesticides_and_fruit.html http://thelastpsychiatrist.com/2010/01/is_genetically_modified_food_s.html