RichardKennaway comments on Friendly to the Extreme: Kids and Adults With Williams Syndrome (Link) - Less Wrong Discussion
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I'm not sure how much you're agreeing or disagreeing there. To me, the mental deficits of Williams Syndrome are the showstopper. There are lots of other ways in which people can and do vary, and where we happen to be on those scales isn't necessarily the way we would have to be, to have got here at all.
Williams Syndrome isn't all or nothing, BTW. Some anecdotal data.