I know people who specifically said that if orgasmium were available, they'd take it in an instant. I also know people that would not. Wireheading doesn't have to be univerally, objectively "good" or "bad." If wireheading would satisfy all your values, and it becomes available to you, well, go for it.

I know that if I was given access to orgasmium, I'd probably be content living on it for the rest of my life. That doesn't change the fact that BEFORE having access to orgasmium, I simply prefer not to accept it, and instead create art and discover things. That's my personal preference.

I've actually considered that, even ignoring the orgasmium element, I could probably self modify into a person who doesn't care about accomplishing stressful art projects, who just does things that make him immediately happy. But my eventual response to myself: I'm the sort of person who prefers not to self modify into that kind of person. No, I don't need to be able to justify that to anyone else, I just need to feel that way.