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Phocion comments on Should I get genotyped? - Less Wrong Discussion

7 Post author: jsalvatier 24 October 2011 03:51PM

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Comment author: Phocion 01 November 2011 04:18:49AM 0 points [-]

With the large number of genetic diseases that exist, it seems improbable that neither you nor your partner would be a carrier for something. So your statement would imply that most couples should use embryo screening, and possibly go through thousands of embryos to find one that is free of any genetic defects. This seems both unnecessarily costly and also unwise- without knowing more about the human genome, we can't be sure that eliminating a defect wouldn't cause worse problems. For example, we know that carriers of sickle-cell anemia are more resistant to malaria. What other correlations would we miss through haphazardly screening out carriers of other diseases?

Of course, in a case like cystic fibrosis, embryo selection is the clear choice.