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lessdazed comments on Disability Culture Meets the Transhumanist Condition - Less Wrong Discussion
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Arguments about how things would be ceteris paribus don't translate well into policy suggestions.
They can still be relevant when we're not talking about any particular person, though. They're especially relevant when we're discussing future people, who we can't come to a good understanding of but must decide whether or not to affect anyway.
Which isn't to say that we can't take other factors into account too.