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ZankerH comments on Humans Shouldn't make Themselves Smarter? - Less Wrong Discussion
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Of course, that assumes that autism should be considered a mental disorder. Many of those on the autism spectrum don't, whereas most of those with depression or high levels of anxiety do consider their condition to be a disorder. It looks a lot to me like status quo bias: if being more intelligent will cause our minds to become qualitatively different then we shouldn't try to be more intelligent.
Then again, defining disorders by self-reporting isn't that much more accurate than going with "any mental condition considered weird by the society".
But that is how a lot of mental disorders are defined. See: attempts to medicalise non-heterosexuality.