It's not particularly failing me relative to my expectations. And why does he use, say, the Pfizer executive's expectations as an example of something that science is failing by? "Our expectations" seems suspiciously similar to "all expectations ever." Or, more likely, "expectations the author thought it would be a good idea to have had of science when writing the article."
Well, most people seem to be surprised that the majority of medical science results (or at least a high percentage) turns out to be bogus.
Jonah Lehrer has up another of his contrarian science articles: "Trials and Errors: Why Science Is Failing Us".
Main topics: the failure of drugs in clinical trials, diminishing returns to pharmaceutical research, doctors over-treating, and Humean causality-correlation distinction, with some Ioannidis mixed through-out.
See also "Why epidemiology will not correct itself"
In completely unrelated news, Nick Bostrom is stepping down from IEET's Chairman of the Board.