The practice in the US of alerting people in the neighbourhood to the presence of convicted child molesters (or was it rapists? I don't remember) seems to indicate that at least some people think that it's a great idea. I think that as we get better at testing people for sociopathy we're likely to move towards certain types of legal discrimination towards them too.

None of this affects my personal ideas of equality though. I would prefer not to be friends with an evil megalomaniac in the same way that I would prefer not to be friends with a drug addict, but if I met an interesting person and then discovered that they were an evil megalomaniacal drug addict I wouldn't necessarily cut them out of my life, either.