If you are older you should definitely be focusing on strategies for biological life extension (calorie restriction, or whatever), and everyone should sign up for cryonics as an insurance policy.

Ultimately, with full molecular nanotechnology, whether the engineering of negligible senescence is biological or digital is rather beside the point ("What exactly do you mean by ‘machine’, such that humans are not machines?" - Eliezer Yudkowsky).

However, Unfriendly AI would render the whole point moot. So the most important thing is to guarantee we get Friendly AI right.