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CronoDAS comments on Harry Potter and the Methods of Rationality discussion thread, part 14, chapter 82 - Less Wrong Discussion
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A lethal dose of botulinum toxin is indeed tiny; using it as an Ultimate Weapon, though, requires a delivery system.
Which is also easy with magic.
Probably; magic makes everything easier, but you still have to find a way to get the people you want to eat it, inhale it, or get it into their bloodstream, and the Harry Potter world isn't defined well enough to give an obvious way to distribute it in such a way that, say, wearing a gas mask and only eating thoroughly cooked food wouldn't defeat.
Gas mask? That doesn't defeat the most obvious distribution mechanism: transfiguration into oxygen or nitrogen. But of course this would require an actual source of botox. If trying to use transfiguration as an ultimate weapon purely in the sense of 'creating stuff for free' (rather than untransfiguring stuff inside folks) it would be far simpler to transfigure something into radioactive isotopes of common airborne gasses. Oxygen-15 seems like it has a half-life in the right ballpark.
Or just transmute cyanide into oxygen. Or their face into cyanide.
I think we have well and truly established that the untransmute-from-gas-hack constitutes a superweapon - whether you use botox, cyanide or rocks. The context, however, was exploring the possibility of using tranmutation itself (without untransmutation) to create powerful weapons (such as botox). Whether the poison you consider is botox or cyanide you can either use transmutation to create it or transmutation to deliver it past the gas masks but not both. In that context the task is to create a lethal substance that can be devilvered easily.
If only time travel wasn't limited to 6 hours. Then the natural improvement would have been "Or their mom's face into cyanide". As it happens, though, we are left with considering "transmute their face into cyanide" as a line of sight attack spell. But as Quirrell's explained in his first battle magic class the best spell for that role is pretty much always avada kedavra.
Except that can be dodged. How do you dodge transmutation? It's been established that it has been used in combat by an expert duelist(albeit incredibly dangerously), so I'd wager that it's not without use.
You make sure your opponent doesn't touch you with his wand.
Huh, somehow I missed that restriction.
wedrifid did it first.
You transfigure (a one atom line in the air to the person and his face) to cyanide.
Harry can do partial transfiguration; he can't transfigure gases.