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Emile comments on Why I Moved from AI to Neuroscience, or: Uploading Worms - Less Wrong Discussion
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He mentions that in the video - there's a list of stereotypical behaviors, when X happens the worm turns around, etc. Having the simulation behave the same way would be a good sign.
He also mentions zapping neurons to see what happens without them; though I'm less sure if that is to be used as an additional test of model validity, or just as a way to figure out which neurons do what.