Sure. Relatedly, the Mona Lisa currently hanging in the Louvre isn't the original... that only existed in the early 1500s. All we have now is the 500-year-old descendent of the original Mona Lisa, which is not the same, it is merely a descendent.
Fortunately for art collectors, human biases are such that the 500-year-old descendent is more valuable in most people's minds than the original would be.
I'd rather have the early original-- I'd like to see the colors Leonardo intended, though I suppose he was such a geek that he might have tweaked them to allow for some fading.
Paint or Pixel: The Digital Divide in Illustration Art has more than a little (and more than I read) about what collecting means when some art is wholly or partially digital. Some artists sell a copy of the process by which the art was created, and some make a copy in paint of the digital original.
Strange but true: making digital art is more physically wearing than using paintbrushes...
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.