You're looking at Less Wrong's discussion board. This includes all posts, including those that haven't been promoted to the front page yet. For more information, see About Less Wrong.

gwern comments on Value of Information: 8 examples - Less Wrong Discussion

48 Post author: gwern 18 May 2012 11:45PM

You are viewing a comment permalink. View the original post to see all comments and the full post content.

Comments (43)

You are viewing a single comment's thread. Show more comments above.

Comment author: gwern 26 May 2013 09:14:57PM 0 points [-]

How has the experiment been going?

Comment author: CasioTheSane 05 June 2013 06:50:33AM *  0 points [-]

Hey gwern, as you predicted I didn't have enough data to learn anything... and I didn't have time to do it longer. I considered repeating it, but now I'm scared off melatonin until I learn more about how it works. Dr. Ray Peat theorizes that it might have some negative health effects by inhibiting oxidative metabolism:

http://www.google.com/cse?cx=005233684413389937395%3Ad5qfhqsz7oo&ie=UTF-8&q=melatonin#gsc.tab=0&gsc.q=melatonin&gsc.page=1

Also, anecdotally I don't really see a huge benefit to melatonin. Even small doses (0.75mg) seem to make me slightly groggy when I wake 7.5 hours later. I may have unusually slow melatonin metabolism, as I have the "slow caffeine metabolizer" P450 CYP1A2 variant, the same enzyme responsible for clearing melatonin.