The dangers of decompartmentalising toxic waste have been covered here before: Phil Goetz's classic Reason as memetic immune disorder. Vladimir Nesov hypothesises that this is why humans compartmentalise.

In the skepticsphere, decompartmentalising stupidity is considered the best hypothesis to explain the Salem hypothesis: that if a creationist touts scientific expertise in a supporter, said supporter is likely an engineer. But engineers in general are notorious for this sort of thing.