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Vaniver comments on Ekman Training - Reviews and/or Testing - Less Wrong Discussion
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What is the smallest effect size you would be able to reliably detect with a test that small?
Unfortunately I have no idea. My statistics knowledge is many years unused.... I have some brushing up to do.
But it seems you're right - if each person gave 50 statements, the sample size would just be 250 (the # of liers x the number of statements they give).