Cryonics is still my favorite. Some reasons:
The second most interesting to me is whole body replacement or "brain in a jar" technology. Since it would be a less complex system than the whole body and designed more according to human intuitions, I would expect such a system to be easier to maintain indefinitely than the body itself. The brain itself is a less complex system than the body as a whole, so neural aging seems like it should be less complex than whole-body aging.
It is also easier to perform cryonics on an isolated brain than a whole body, for physical and biological reasons. The exact concentrations of cryoprotectant can be fine-tuned to the brain, and the cooling rate is better for a detached head or brain than a body. Removing cryoprotectants and rewarming at the optimal rate should also be easier. Thus when it happens, it is reasonable to expect the first successful reanimations to be not of whole bodies but individual brains.
For those who are interested in this topic, I'm just wondering what longevity research today looks most promising to you and why. Whether that's SENS, cryonics, nanotech, brain uploading, etc is fine with me. Any links to actual research papers would also be greatly appreciated. I'm very interested in longevity, and am curious to see if anyone else would like to offer some thoughts on the current state of the art.