Aside from the sensationalism, these results are a stunning and unequivocal endorsement that the scientific system works.
2047 articles retracted (for any reason) out of 25 million = 0.008%. (Edit: I mistyped the figure as 5 million instead of 25 million, but the percentage was correct.) 21.3% of that was retracted due to error, i.e. 0.0017% of all published papers later admitted an error that made the paper worthless.
That looks like massive underreporting. I cannot believe that there weren't several orders of magnitude more retraction-worthy cases, which were not retracted. In fact, this is so massive that I would characterize it as unequivocal endorsement that the scientific system is broken, because nobody is willing to admit to their (honest, non fraudulent) errors, and few publish failed reproductions.
Analyzing the few papers that were retracted will surely have big confounding factors, because it's a preselected subset of papers that is already abnormal in some way (why were they retracted? Did a third party discover the fraud? Is this selection for the least competent fraudsters?)
What rate of retraction would provide evidence that the system is working?
From Gene Expression by Razib Khan who some of you may also know from the old gnxp site or perhaps from his BHTV debate with Eliezer.
Link to original post.