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ChristianKl comments on Rationality, Transhumanism, and Mental Health - Less Wrong Discussion
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Cannabis is schedule I, ketamine isn't. I therefore don't see the point of bringing up cannabis.
The previous comment of mine was an example of a controversial move by the FDA, which illustrates that they may have reasons to deny approval to certain drugs deemed to have excessive "recreational" potential. I'm hoping you can see why this is relevant to a conversation about why the FDA might opt not to approve a drug....
Why do you focus on the FDA? Almost all countries have drug regulation agencies, and various of them approve cannabis or cannabinoids for therapeutic uses, but, as far as I know, none of them approves ketamine for use as an antidepressant.
Because the thread was about the FDA. I have no clue whether the claim about ketamine is valid or not, but I do strongly suspect that "The FDA has not approved this" is not relevant (since they have a clear motive to oppose the substance even if it is an antidepressant.)
If no place else has approved it, then that is much more useful evidence against ketamine, and I'm glad to encounter such :)