Fair enough. Can I take your point to be "when things get super complicated, sometimes you can make conceptual progress only by not worrying about keeping track of everything?" The only trouble is that once you stop keeping track of probability/significance, it becomes difficult to pick it up again in the future - you'd need to gather additional evidence in a better-understood way to check what's going on. Actually, that's a good analogy for hypothesis generation, with the "difficult to keep track of" stuff becoming the problem of uncertain priors.